Aging mechanisms—A perspective mostly from Drosophila
نویسندگان
چکیده
منابع مشابه
Healthy Aging – Insights from Drosophila
Human life expectancy has nearly doubled in the past century due, in part, to social and economic development, and a wide range of new medical technologies and treatments. As the number of elderly increase it becomes of vital importance to understand what factors contribute to healthy aging. Human longevity is a complex process that is affected by both environmental and genetic factors and inte...
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Flies of the genus Drosophila, particularly D. melanogaster, have been mainstays of biological research on aging for more than 80 years. However, what was striking for most of those years was how little concrete progress was made on the problem of aging using the normally powerful Drosophila model system. To be sure, a great deal of longitudinal information was accumulated about Drosophila agin...
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In a variety of organisms, adulthood is divided into aging and late life, where aging is a period of exponentially increasing mortality rates and late life is a period of roughly plateaued mortality rates. In this study we used ∼57,600 Drosophila melanogaster from six replicate populations to examine the physiological transitions from aging to late life in four functional characters that declin...
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ژورنال
عنوان ژورنال: Advanced Genetics
سال: 2020
ISSN: 2641-6573,2641-6573
DOI: 10.1002/ggn2.10026